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Vacuole Size Control: Regulation of PtdIns(3,5)P(2) Levels by the Vacuole-associated Vac14-Fig4 Complex, a PtdIns(3,5)P(2)-specific Phosphatase
In the budding yeast Saccharomyces cerevisiae, phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P(2)) is synthesized by a single phosphatidylinositol 3-phosphate 5-kinase, Fab1. Cells deficient in PtdIns(3,5)P(2) synthesis exhibit a grossly enlarged vacuole morphology, whereas increased levels of P...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The American Society for Cell Biology
2004
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC307524/ https://ncbi.nlm.nih.gov/pubmed/14528018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-05-0297 |
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