Conversion of PtdIns(4,5)P(2) into PtdIns(5)P by the S.flexneri effector IpgD reorganizes host cell morphology

Phosphoinositides play a central role in the control of several cellular events including actin cytoskeleton organization. Here we show that, upon infection of epithelial cells with the Gram-negative pathogen Shigella flexneri, the virulence factor IpgD is translocated directly into eukaryotic cells...

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Main Authors: Niebuhr, Kirsten, Giuriato, Sylvie, Pedron, Thierry, Philpott, Dana J., Gaits, Frédérique, Sable, Julia, Sheetz, Michael P., Parsot, Claude, Sansonetti, Philippe J., Payrastre, Bernard
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2002
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC129044/
https://ncbi.nlm.nih.gov/pubmed/12356723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf522
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