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Conversion of PtdIns(4,5)P(2) into PtdIns(5)P by the S.flexneri effector IpgD reorganizes host cell morphology

Phosphoinositides play a central role in the control of several cellular events including actin cytoskeleton organization. Here we show that, upon infection of epithelial cells with the Gram-negative pathogen Shigella flexneri, the virulence factor IpgD is translocated directly into eukaryotic cells...

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Detalhes bibliográficos
Publicado no:EMBO J
Principais autores: Niebuhr, Kirsten, Giuriato, Sylvie, Pedron, Thierry, Philpott, Dana J., Gaits, Frédérique, Sable, Julia, Sheetz, Michael P., Parsot, Claude, Sansonetti, Philippe J., Payrastre, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC129044/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12356723/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf522
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