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Vacuole Size Control: Regulation of PtdIns(3,5)P(2) Levels by the Vacuole-associated Vac14-Fig4 Complex, a PtdIns(3,5)P(2)-specific Phosphatase

In the budding yeast Saccharomyces cerevisiae, phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P(2)) is synthesized by a single phosphatidylinositol 3-phosphate 5-kinase, Fab1. Cells deficient in PtdIns(3,5)P(2) synthesis exhibit a grossly enlarged vacuole morphology, whereas increased levels of P...

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Detalhes bibliográficos
Main Authors: Rudge, Simon A., Anderson, Deborah M., Emr, Scott D.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC307524/
https://ncbi.nlm.nih.gov/pubmed/14528018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-05-0297
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