COX-2 blockade suppresses gliomagenesis by inhibiting myeloid-derived suppressor cells

Epidemiological studies have highlighted associations between the regular use of nonsteroidal anti-inflammatory drugs (NSAIDs) and reduced glioma risks in humans. Most NSAIDs function as cyclooxygenase-2 (COX-2) inhibitors that prevent production of prostaglandin E(2) (PGE(2)). Since PGE(2) induces...

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Detalhes bibliográficos
Main Authors: Fujita, Mitsugu, Kohanbash, Gary, Fellows-Mayle, Wendy, Hamilton, Ronald L., Komohara, Yoshihiro, Decker, Stacy A., Ohlfest, John R., Okada, Hideho
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075086/
https://ncbi.nlm.nih.gov/pubmed/21324923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-3055
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