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IT-17 ONO-AE3-208 INHIBITS MYELOID-DERIVED SUPPRESSOR CELLS AND GLIOMA GROWTH
Myeloid-Derived Suppressor Cells (MDSCs) heavily infiltrate in a variety of solid tumors and suppress anti-tumor T-cell activity. Our recent studies have demonstrated the ability of monocytic, Ly6C(+) MDSCs to promote glioma growth through the activation of cyclooxygenase (COX)-2 pathway, which is r...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4218233/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou258.15 |
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