IT-17 ONO-AE3-208 INHIBITS MYELOID-DERIVED SUPPRESSOR CELLS AND GLIOMA GROWTH

Myeloid-Derived Suppressor Cells (MDSCs) heavily infiltrate in a variety of solid tumors and suppress anti-tumor T-cell activity. Our recent studies have demonstrated the ability of monocytic, Ly6C(+) MDSCs to promote glioma growth through the activation of cyclooxygenase (COX)-2 pathway, which is r...

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Hlavní autoři: Kohanbash, Gary, Straw, Erin, Averick, Amram, Ahn, Brian, Smith-Cohn, Matthew, Ohkuri, Takayuki, Kosaka, Akemi, Okada, Hideho
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218233/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou258.15
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