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Role of type-1 interferons in anti-glioma immunosurveillance - Using mouse studies to guide examination of novel prognostic markers in humans
PURPOSE: We hypothesized that the type-1 interferons (IFNs) would play a pivotal role in anti-glioma immunosurveillance through promotion of type-1 adaptive immunity and suppression of immunoregulatory cells. EXPERIMENTAL DESIGN: We induced de novo gliomas in Ifnar1(−/−) (deficient for type-1 IFN re...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2896455/ https://ncbi.nlm.nih.gov/pubmed/20472682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-0644 |
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