Interdependence of HIF-1α and TGF-β/Smad3 signaling in normoxic and hypoxic renal epithelial cell collagen expression

Increasing evidence suggests that chronic kidney disease may develop following acute kidney injury and that this may be due, in part, to hypoxia-related phenomena. Hypoxia-inducible factor (HIF) is stabilized in hypoxic conditions and regulates multiple signaling pathways that could contribute to re...

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Autores principales: Basu, Rajit K., Hubchak, Susan, Hayashida, Tomoko, Runyan, Constance E., Schumacker, Paul T., Schnaper, H. William
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2011
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075002/
https://ncbi.nlm.nih.gov/pubmed/21209004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00335.2010
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