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Interdependence of HIF-1α and TGF-β/Smad3 signaling in normoxic and hypoxic renal epithelial cell collagen expression

Increasing evidence suggests that chronic kidney disease may develop following acute kidney injury and that this may be due, in part, to hypoxia-related phenomena. Hypoxia-inducible factor (HIF) is stabilized in hypoxic conditions and regulates multiple signaling pathways that could contribute to re...

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Detalhes bibliográficos
Main Authors: Basu, Rajit K., Hubchak, Susan, Hayashida, Tomoko, Runyan, Constance E., Schumacker, Paul T., Schnaper, H. William
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075002/
https://ncbi.nlm.nih.gov/pubmed/21209004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00335.2010
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