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Interdependence of HIF-1α and TGF-β/Smad3 signaling in normoxic and hypoxic renal epithelial cell collagen expression

Increasing evidence suggests that chronic kidney disease may develop following acute kidney injury and that this may be due, in part, to hypoxia-related phenomena. Hypoxia-inducible factor (HIF) is stabilized in hypoxic conditions and regulates multiple signaling pathways that could contribute to re...

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Bibliographische Detailangaben
Hauptverfasser: Basu, Rajit K., Hubchak, Susan, Hayashida, Tomoko, Runyan, Constance E., Schumacker, Paul T., Schnaper, H. William
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075002/
https://ncbi.nlm.nih.gov/pubmed/21209004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00335.2010
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