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Hippocampal-Dependent Antidepressant-Like Activity of Histone Deacetylase Inhibition

Chronic social defeat stress in mice significantly decreases subsequent social interactions and induces other depression-like behaviors. Here we measured and manipulated levels of acetylated histone H3 (acH3), a chromatin mark of transcriptional activation, in the hippocampus and amygdala after ten...

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Sonraí Bibleagrafaíochta
Main Authors: Covington, Herbert E., Vialou, Vincent F., LaPlant, Quincey C., Ohnishi, Yoshinori N., Nestler, Eric J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074929/
https://ncbi.nlm.nih.gov/pubmed/21335060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2011.02.022
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