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Asymmetric synthesis of enantiopure isoxazolidinone monomers for the synthesis of β(3)-oligopeptides by chemoselective amide ligation

The design and general synthesis of enantiopure isoxazolidinone monomers as precursors for the preparation of enantiopure N-terminal hydroxylamine—β(3)-oligopeptides, which may be used as reaction partners with α-ketoacids in the decarboxylative amide ligation reaction, is described.

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書誌詳細
主要な著者: Juarez-Garcia, M. Elisa, Yu, Shouyun, Bode, Jeffrey W.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074535/
https://ncbi.nlm.nih.gov/pubmed/21499500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2010.04.016
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