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Asymmetric synthesis of enantiopure isoxazolidinone monomers for the synthesis of β(3)-oligopeptides by chemoselective amide ligation
The design and general synthesis of enantiopure isoxazolidinone monomers as precursors for the preparation of enantiopure N-terminal hydroxylamine—β(3)-oligopeptides, which may be used as reaction partners with α-ketoacids in the decarboxylative amide ligation reaction, is described.
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3074535/ https://ncbi.nlm.nih.gov/pubmed/21499500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2010.04.016 |
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