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B cell- and BAFF-dependence of IFNα-exaggerated disease in SLE-prone NZM 2328 mice
IFNα is a potent activator of innate and adaptive immunity, and its administration to pre-autoimmune (NZBxNZW)F1 mice promotes virulent systemic lupus erythematosus (SLE) disease. Given the known contributions of B cells and BAFF to SLE, we evaluated the ability of IFNα administration to induce dise...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3074466/ https://ncbi.nlm.nih.gov/pubmed/21383240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000466 |
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