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Selective involvement of BH3-only proteins and differential targets of Noxa in diverse apoptotic pathways
The BH3-only proteins of the Bcl-2 family are known to mediate mitochondrial dysfunction during apoptosis. However, the identity of the critical BH3-only proteins and the mechanism of their action following treatment by diverse apoptotic stimuli remain to be fully resolved. We therefore used RNAi to...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3074052/ https://ncbi.nlm.nih.gov/pubmed/21113147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.152 |
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