Selective involvement of BH3-only proteins and differential targets of Noxa in diverse apoptotic pathways

The BH3-only proteins of the Bcl-2 family are known to mediate mitochondrial dysfunction during apoptosis. However, the identity of the critical BH3-only proteins and the mechanism of their action following treatment by diverse apoptotic stimuli remain to be fully resolved. We therefore used RNAi to...

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Главные авторы: Zhang, L, Lopez, H, George, N M, Liu, X, Pang, X, Luo, X
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2011
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Original Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074052/
https://ncbi.nlm.nih.gov/pubmed/21113147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.152
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