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A Model of a MAPK•Substrate Complex in an Active Conformation: A Computational and Experimental Approach

The mechanisms by which MAP kinases recognize and phosphorylate substrates are not completely understood. Efforts to understand the mechanisms have been compromised by the lack of MAPK-substrate structures. While MAPK-substrate docking is well established as a viable mechanism for bringing MAPKs and...

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Bibliografische gegevens
Hoofdauteurs: Lee, Sunbae, Warthaka, Mangalika, Yan, Chunli, Kaoud, Tamer S., Piserchio, Andrea, Ghose, Ranajeet, Ren, Pengyu, Dalby, Kevin N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073974/
https://ncbi.nlm.nih.gov/pubmed/21494553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018594
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