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Signaling in thymic selection

T cell receptor signaling allows the developing thymocyte to undergo positive or negative selection, which are required for formation of a useful mature T cell repertoire. Recent developments include the finding that much of the Lck kinase (required to initiate T cell signaling) is already in an act...

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Detalhes bibliográficos
Main Authors: Gascoigne, Nicholas R.J., Palmer, Ed
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073816/
https://ncbi.nlm.nih.gov/pubmed/21242076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2010.12.017
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