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Id1 immortalizes hematopoietic progenitors in vitro and promotes a myeloproliferative disease in vivo

Id1 is frequently overexpressed in many cancer cells, but the functional significance of these findings is not known. To determine if Id1 could contribute to the development of hematopoietic malignancy, we reconstituted mice with hematopoietic cells overexpressing Id1. We showed for the first time t...

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Bibliografische gegevens
Hoofdauteurs: Suh, HC, Leeanansaksiri, W, Ji, M, Klarmann, KD, Renn, K, Gooya, J, Smith, D, McNiece, I, Lugthart, S, Valk, PJM, Delwel, R, Keller, JR
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073486/
https://ncbi.nlm.nih.gov/pubmed/18542061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.175
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