C/EBPα determines hematopoietic cell fate in multipotential progenitor cells by inhibiting erythroid differentiation and inducing myeloid differentiation

C/EBPα is an essential transcription factor required for myeloid differentiation. While C/EBPα can act as a cell fate switch to promote granulocyte differentiation in bipotential granulocyte-macrophage progenitors (GMPs), its role in regulating cell fate decisions in more primitive progenitors is no...

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Bibliografiska uppgifter
Huvudupphovsmän: Suh, Hyung Chan, Gooya, John, Renn, Katie, Friedman, Alan D., Johnson, Peter F., Keller, Jonathan R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society of Hematology 2006
Ämnen:
Hematopoiesis
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895788/
https://ncbi.nlm.nih.gov/pubmed/16469877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-06-2216
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