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Id1 immortalizes hematopoietic progenitors in vitro and promotes a myeloproliferative disease in vivo
Id1 is frequently overexpressed in many cancer cells, but the functional significance of these findings is not known. To determine if Id1 could contribute to the development of hematopoietic malignancy, we reconstituted mice with hematopoietic cells overexpressing Id1. We showed for the first time t...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3073486/ https://ncbi.nlm.nih.gov/pubmed/18542061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.175 |
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