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Bypass of Senescence, Immortalization, and Transformation of Human Hematopoietic Progenitor Cells
We attempted to extend the lifespan of CD34(+) stem/progenitor cells in human cord blood (CB) by transduction with entiviral vectors carrying the human telomerase catalytic subunit (hTERT) and/or the human papillomavirus type 16 (HPV16) E6 and E7 oncogenes. We found that hTERT was incapable of prolo...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1360608/ https://ncbi.nlm.nih.gov/pubmed/16144874 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/stemcells.2005-0390 |
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