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Methylome of human senescent hematopoietic progenitors

Abstract Senescence, a state of permanent cell cycle arrest, can be induced by DNA damage. This process, which was initially described in fibroblasts, is now recognized to occur in stem cells. It has been well characterized in cell lines, but there is currently very limited data available on human s...

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Detalhes bibliográficos
Main Authors: Stephen Capone, Anthony R. Colombo, Benjamin K. Johnson, Tim J. Triche, Giridharan Ramsingh
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2018-12-01
Colecção:Experimental Hematology & Oncology
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Acesso em linha:http://link.springer.com/article/10.1186/s40164-018-0123-8
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