A comprehensive methylome map of lineage commitment from hematopoietic progenitors

Epigenetic modifications must underlie lineage-specific differentiation as terminally differentiated cells express tissue-specific genes, but their DNA sequence is unchanged. Hematopoiesis provides a well-defined model to study epigenetic modifications during cell-fate decisions, as multipotent prog...

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Main Authors: Ji, Hong, Ehrlich, Lauren I. R., Seita, Jun, Murakami, Peter, Doi, Akiko, Lindau, Paul, Lee, Hwajin, Aryee, Martin J., Irizarry, Rafael A., Kim, Kitai, Rossi, Derrick J, Inlay, Matthew A., Serwold, Thomas, Karsunky, Holger, Ho, Lena, Daley, George Q., Weissman, Irving L., Feinberg, Andrew P.
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956609/
https://ncbi.nlm.nih.gov/pubmed/20720541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09367
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