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A comprehensive methylome map of lineage commitment from hematopoietic progenitors
Epigenetic modifications must underlie lineage-specific differentiation as terminally differentiated cells express tissue-specific genes, but their DNA sequence is unchanged. Hematopoiesis provides a well-defined model to study epigenetic modifications during cell-fate decisions, as multipotent prog...
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| Main Authors: | , , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2956609/ https://ncbi.nlm.nih.gov/pubmed/20720541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09367 |
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