A comprehensive methylome map of lineage commitment from hematopoietic progenitors

Epigenetic modifications must underlie lineage-specific differentiation as terminally differentiated cells express tissue-specific genes, but their DNA sequence is unchanged. Hematopoiesis provides a well-defined model to study epigenetic modifications during cell-fate decisions, as multipotent prog...

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Bibliografiset tiedot
Päätekijät: Ji, Hong, Ehrlich, Lauren I. R., Seita, Jun, Murakami, Peter, Doi, Akiko, Lindau, Paul, Lee, Hwajin, Aryee, Martin J., Irizarry, Rafael A., Kim, Kitai, Rossi, Derrick J, Inlay, Matthew A., Serwold, Thomas, Karsunky, Holger, Ho, Lena, Daley, George Q., Weissman, Irving L., Feinberg, Andrew P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956609/
https://ncbi.nlm.nih.gov/pubmed/20720541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09367
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