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Bypass of Senescence, Immortalization, and Transformation of Human Hematopoietic Progenitor Cells

We attempted to extend the lifespan of CD34(+) stem/progenitor cells in human cord blood (CB) by transduction with entiviral vectors carrying the human telomerase catalytic subunit (hTERT) and/or the human papillomavirus type 16 (HPV16) E6 and E7 oncogenes. We found that hTERT was incapable of prolo...

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Autors principals: Akimov, Sergey S., Ramezani, Ali, Hawley, Teresa S., Hawley, Robert G.
Format: Artigo
Idioma:Inglês
Publicat: 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360608/
https://ncbi.nlm.nih.gov/pubmed/16144874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/stemcells.2005-0390
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