Synthesis and biological activities of a phosphorodithioate analog of 2',5'-oligoadenylate.
To enhance the resistance of 2-5A (pppA2'p5'A2'p5'A) to degradation by exo- and endonucleases, a phosphorodithioate analog was synthesized using a solid-phase phosphite triester approach with N6-benzoyl-5'-O-dimethoxytrityl-3'-O-t-butyldimethylsilyladenosine 2'-[S-(beta-thiobenzoylethyl)-pyrrolidino...
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| Опубліковано в:: | Nucleic Acids Res |
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| Автори: | , , , , , , , |
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Oxford University Press
1995
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| Онлайн доступ: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307321/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479047/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.19.3989 |
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