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Liver Kinase B1 (LKB1) in the Pathogenesis of UVB-induced Murine Basal Cell Carcinoma
LKB1, a known tumor suppressor, is mutated in Peutz-Jeghers Syndrome (PJS). It is responsible for the enhanced cancer risk in patients with PJS. Dysregulation of LKB1-dependent signaling also occurs in various epithelial cancers. UVB alters the expression of LKB1, though its role in the pathogenesis...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3072754/ https://ncbi.nlm.nih.gov/pubmed/21272562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2011.01.006 |
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