Leishmania major Attenuates Host Immunity by Stimulating Local Indoleamine 2,3-Dioxygenase Expression

Inflammation stimulates immunity but can create immune privilege in some settings. Here, we show that cutaneous Leishmania major infection stimulated expression of the immune regulatory enzyme indoleamine 2,3 dioxygenase (IDO) in local lymph nodes. Induced IDO attenuated the T cell stimulatory funct...

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Bibliografiset tiedot
Päätekijät: Makala, Levi H. C., Baban, Babak, Lemos, Henrique, El-Awady, Ahmed R., Chandler, Phillip R., Hou, De-Yan, Munn, David H., Mellor, Andrew L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2011
Aiheet:
Major Articles and Brief Reports
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072725/
https://ncbi.nlm.nih.gov/pubmed/21282196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiq095
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