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The soluble form of Bax regulates mitochondrial fusion via MFN2 homotypic complexes
In mammals, fusion of the mitochondrial outer membrane is controlled by two DRPs, MFN1 and MFN2, that function in place of a single outer membrane DRP, Fzo1 in yeast. We addressed the significance of two mammalian outer membrane fusion DRPs using an in vitro mammalian mitochondrial fusion assay. We...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3072068/ https://ncbi.nlm.nih.gov/pubmed/21255726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.11.030 |
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