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Defective nucleotide-dependent assembly and membrane fusion in Mfn2 CMT2A variants improved by Bax
Mitofusins are members of the dynamin-related protein family of large GTPases that harness the energy from nucleotide hydrolysis to remodel membranes. Mitofusins possess four structural domains, including a GTPase domain, two extended helical bundles (HB1 and HB2), and a transmembrane region. We hav...
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| Veröffentlicht in: | Life Sci Alliance |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Life Science Alliance LLC
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7136618/ https://ncbi.nlm.nih.gov/pubmed/32245838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201900527 |
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