Llwytho...
Visualizing a one-way protein encounter complex by ultrafast single-molecule mixing
We combined rapid microfluidic mixing with single-molecule Förster Resonance Energy Transfer to study the folding kinetics of the intrinsically disordered human protein α-synuclein. The time-resolution of 0.2 ms revealed initial collapse of the unfolded protein induced by binding with lipid-mimics a...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2011
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3071799/ https://ncbi.nlm.nih.gov/pubmed/21297620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1568 |
| Tagiau: |
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