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Differential Response to Morphine of the Oligomeric State of μ-Opioid in the Presence of δ-Opioid Receptors

Prolonged morphine treatment induces extensive desensitization of the μ-opioid receptor (μOR) which is the G protein-coupled receptor that primarily mediates the cellular response to morphine. To date, the molecular mechanism underlying this process is unknown. Here, we have used live cell fluoresce...

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Bibliografiske detaljer
Main Authors: Golebiewska, Urszula, Johnston, Jennifer M., Devi, Lakshmi, Filizola, Marta, Scarlata, Suzanne
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071705/
https://ncbi.nlm.nih.gov/pubmed/21361347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101701x
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