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Differential Stability of the Crystallographic Interfaces of Mu- and Kappa-Opioid Receptors

The recent mu-opioid receptor (MOPr) and kappa-opioid receptor (KOPr) crystal structures have inspired hypotheses of physiologically relevant dimerization contacts, specifically: a closely packed interface involving transmembrane (TM) helices TM5 and TM6, and a less compact interface, involving TM1,...

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Bibliographic Details
Main Authors: Johnston, Jennifer M., Filizola, Marta
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944890/
https://ncbi.nlm.nih.gov/pubmed/24651466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090694
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