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Differential Stability of the Crystallographic Interfaces of Mu- and Kappa-Opioid Receptors
The recent mu-opioid receptor (MOPr) and kappa-opioid receptor (KOPr) crystal structures have inspired hypotheses of physiologically relevant dimerization contacts, specifically: a closely packed interface involving transmembrane (TM) helices TM5 and TM6, and a less compact interface, involving TM1,...
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Formato: | Artigo |
Idioma: | Inglês |
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Public Library of Science
2014
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3944890/ https://ncbi.nlm.nih.gov/pubmed/24651466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090694 |
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