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Obesity is associated with inflammation and elevated aromatase expression in the mouse mammary gland

Elevated circulating estrogen levels are associated with increased risk of breast cancer in obese postmenopausal women. Following menopause, the biosynthesis of estrogens through CYP19 (aromatase)-mediated metabolism of androgen precursors occurs primarily in adipose tissue, and the resulting estrog...

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Detaylı Bibliyografya
Asıl Yazarlar: Subbaramaiah, Kotha, Howe, Louise R., Bhardwaj, Priya, Du, Baoheng, Gravaghi, Claudia, Yantiss, Rhonda K., Zhou, Xi Kathy, Blaho, Victoria A., Hla, Timothy, Yang, Peiying, Kopelovich, Levy, Hudis, Clifford A., Dannenberg, Andrew J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071249/
https://ncbi.nlm.nih.gov/pubmed/21372033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-10-0381
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