Dietary Polyphenols Suppress Elevated Levels of Proinflammatory Mediators and Aromatase in the Mammary Gland of Obese Mice

In postmenopausal women, obesity is a risk factor for the development of hormone receptor-positive breast cancer driven by estrogen. After menopause, aromatization of androgen precursors in adipose tissue is a major synthetic source of estrogen. Recently, in mouse models and women, we identified an...

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Main Authors: Subbaramaiah, Kotha, Sue, Erika, Bhardwaj, Priya, Du, Baoheng, Hudis, Clifford A., Giri, Dilip, Kopelovich, Levy, Zhou, Xi Kathy, Dannenberg, Andrew J.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767430/
https://ncbi.nlm.nih.gov/pubmed/23880231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-13-0140
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