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The Ribotoxin Restrictocin Recognizes Its RNA Substrate by Selective Engagement of Active Site Residues
[Image: see text] Restrictocin and related fungal endoribonucleases from the α-sarcin family site-specifically cleave the sarcin/ricin loop (SRL) on the ribosome to inhibit translation and ultimately trigger cell death. Previous studies showed that the SRL folds into a bulged-G motif and tetraloop,...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Chemical Society
2011
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3071035/ https://ncbi.nlm.nih.gov/pubmed/21417210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1018336 |
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