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Bile Acids Induce Inflammatory Genes in Hepatocytes: A Novel Mechanism of Inflammation during Obstructive Cholestasis

Inflammation contributes to liver injury during cholestasis. The mechanism by which cholestasis initiates an inflammatory response in the liver, however, is not known. Two hypotheses were investigated in the present studies. First, activation of Toll-like receptor 4 (TLR4), either by bacterial lipop...

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Detaylı Bibliyografya
Asıl Yazarlar: Allen, Katryn, Jaeschke, Hartmut, Copple, Bryan L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Investigative Pathology 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070591/
https://ncbi.nlm.nih.gov/pubmed/21224055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.11.026
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