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OSTEOPONTIN IS AN INITIAL MEDIATOR OF INFLAMMATION AND LIVER INJURY DURING OBSTRUCTIVE CHOLESTASIS AFTER BILE DUCT LIGATION IN MICE
Osteopontin (OPN) is a chemotactic factor which can be cleaved to the pro-inflammatory form by matrix metalloproteinases (MMPs). To test the hypothesis that OPN can modulate inflammatory liver injury during cholestasis, wild-type (WT) C57BL/6 and OPN knockout (OPN-KO) mice underwent bile duct ligati...
Gorde:
Egile Nagusiak: | , , , , , , , |
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Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
2013
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Gaiak: | |
Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3875222/ https://ncbi.nlm.nih.gov/pubmed/24188933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2013.10.030 |
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