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EFFECT OF BILE DUCT LIGATION ON BILE ACID COMPOSITION IN MOUSE SERUM AND LIVER

BACKGROUND: Cholestatic liver diseases can be caused by genetic defects, drug toxicities, hepatobiliary malignancies or obstruction of the biliary tract. Cholestasis leads to accumulation of bile acids (BAs) in hepatocytes. Direct toxicity of BAs is currently the most accepted hypothesis for cholest...

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Detalhes bibliográficos
Main Authors: Zhang, Youcai, Hong, Ji-Young, Rockwell, Cheryl E., Copple, Bryan L., Jaeschke, Hartmut, Klaassen, Curtis D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263524/
https://ncbi.nlm.nih.gov/pubmed/22098667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1478-3231.2011.02662.x
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