The Ubiquitin Ligase MuRF1 Protects Against Cardiac Ischemia/Reperfusion Injury by Its Proteasome-Dependent Degradation of Phospho-c-Jun

Despite improvements in interventions of acute coronary syndromes, primary reperfusion therapies restoring blood flow to ischemic myocardium leads to the activation of signaling cascades that induce cardiomyocyte cell death. These signaling cascades, including the mitogen-activated protein kinase si...

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Autors principals: Li, Hui-Hua, Du, Jie, Fan, Yong-Na, Zhang, Mei-Li, Liu, De-Pei, Li, Luge, Lockyer, Pamela, Kang, Eunice Y., Patterson, Cam, Willis, Monte S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2011
Matèries:
Regular Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070562/
https://ncbi.nlm.nih.gov/pubmed/21356357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.11.049
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