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The Ubiquitin Ligase MuRF1 Protects Against Cardiac Ischemia/Reperfusion Injury by Its Proteasome-Dependent Degradation of Phospho-c-Jun

Despite improvements in interventions of acute coronary syndromes, primary reperfusion therapies restoring blood flow to ischemic myocardium leads to the activation of signaling cascades that induce cardiomyocyte cell death. These signaling cascades, including the mitogen-activated protein kinase si...

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Hlavní autoři: Li, Hui-Hua, Du, Jie, Fan, Yong-Na, Zhang, Mei-Li, Liu, De-Pei, Li, Luge, Lockyer, Pamela, Kang, Eunice Y., Patterson, Cam, Willis, Monte S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070562/
https://ncbi.nlm.nih.gov/pubmed/21356357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.11.049
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