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Kick-Starting the Ratchet: The Fate of Mutators in an Asexual Population

Muller's ratchet operates in asexual populations without intergenomic recombination. In this case, deleterious mutations will accumulate and population fitness will decline over time, possibly endangering the survival of the species. Mutator mutations, i.e., mutations that lead to an increased...

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Bibliografiske detaljer
Main Authors: Söderberg, R. Jonas, Berg, Otto G.
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070521/
https://ncbi.nlm.nih.gov/pubmed/21288878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.124818
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