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Kick-Starting the Ratchet: The Fate of Mutators in an Asexual Population
Muller's ratchet operates in asexual populations without intergenomic recombination. In this case, deleterious mutations will accumulate and population fitness will decline over time, possibly endangering the survival of the species. Mutator mutations, i.e., mutations that lead to an increased...
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Main Authors: | , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Genetics Society of America
2011
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3070521/ https://ncbi.nlm.nih.gov/pubmed/21288878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.124818 |
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