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Kick-Starting the Ratchet: The Fate of Mutators in an Asexual Population

Muller's ratchet operates in asexual populations without intergenomic recombination. In this case, deleterious mutations will accumulate and population fitness will decline over time, possibly endangering the survival of the species. Mutator mutations, i.e., mutations that lead to an increased...

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Detalhes bibliográficos
Main Authors: Söderberg, R. Jonas, Berg, Otto G.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070521/
https://ncbi.nlm.nih.gov/pubmed/21288878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.124818
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