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The Balance Between Mutators and Nonmutators in Asexual Populations

Mutator alleles, which elevate an individual’s mutation rate from 10 to 10,000-fold, have been found at high frequencies in many natural and experimental populations. Mutators are continually produced from nonmutators, often due to mutations in mismatch-repair genes. These mutators gradually accumul...

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Detalhes bibliográficos
Main Authors: Desai, Michael M., Fisher, Daniel S.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176104/
https://ncbi.nlm.nih.gov/pubmed/21652523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.128116
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