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Kick-Starting the Ratchet: The Fate of Mutators in an Asexual Population

Muller's ratchet operates in asexual populations without intergenomic recombination. In this case, deleterious mutations will accumulate and population fitness will decline over time, possibly endangering the survival of the species. Mutator mutations, i.e., mutations that lead to an increased...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Söderberg, R. Jonas, Berg, Otto G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Genetics Society of America 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070521/
https://ncbi.nlm.nih.gov/pubmed/21288878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.124818
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