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The Aryl-hydrocarbon receptor does not require the p23 co-chaperone for ligand binding and target gene expression in vivo

The Aryl-hydrocarbon receptor (Ahr) is a ligand-activated transcription factor that mediates most of the toxic affects of 2,3,7,8-tetrachlorodibenzo-(p)-dioxin (TCDD) and other xenobiotic compounds. The AHR cytoplasmic complex consists of two molecules of HSP90 and at least one molecule of Hepatitis...

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Détails bibliographiques
Auteurs principaux: Flaveny, Colin, Perdew, Gary H., Miller, Charles A.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070407/
https://ncbi.nlm.nih.gov/pubmed/19447165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2009.05.002
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