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p23 co-chaperone protects the aryl hydrocarbon receptor from degradation in mouse and human cell lines
The aryl hydrocarbon receptor (AhR) is a ligand-sensitive transcription factor which is responsible for most 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicities. Without ligand, the AhR complex is cytoplasmic and contains p23. Our objective was to investigate whether the wild type p23 levels are importan...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3418383/ https://ncbi.nlm.nih.gov/pubmed/22759865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2012.06.018 |
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