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p23 protects the human aryl hydrocarbon receptor from degradation via a heat shock protein 90-independent mechanism

The aryl hydrocarbon receptor (AHR) is a ligand-activated signaling molecule which involves in diverse biological functions ranging from cancer metastasis to immune regulation. This receptor forms a cytoplasmic complex with Hsp90, p23, and XAP2. We have previously reported that down-regulation of p2...

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Detalhes bibliográficos
Publicado no:Biochem Pharmacol
Main Authors: Pappas, Beverly, Yang, Yujie, Wang, Yu, Kim, Kyung, Chung, Hee Jae, Cheung, Michael, Ngo, Katie, Shinn, Annie, Chan, William K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5960609/
https://ncbi.nlm.nih.gov/pubmed/29555469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2018.03.015
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