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Differential Gene Regulation by the Human and Mouse Aryl Hydrocarbon Receptor
The human aryl hydrocarbon receptor (hAHR) and mouse aryl hydrocarbon receptor (mAHR(b)) share limited (58%) transactivation domain (TAD) sequence identity. Compared to the mAHR(b) allele, the hAHR displays 10-fold lower relative affinity for prototypical ligands, such as 2,3,7,8 tetrachlorodibenzo-...
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| Huvudupphovsmän: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Oxford University Press
2010
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2840214/ https://ncbi.nlm.nih.gov/pubmed/20044593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfp308 |
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